There are around five medications which are available in the US only, in one case also Bangladesh (equally difficult to source from), which would be advantageous for me to have access to on semi regular basis; mainly analgesics. My doctor refuses to prescribe any breakthrough//escue meds even though she is well aware that OxyContin has only an average 6hr duration of action in me before I need additional analgesia - certainly nowhere even close to the 12 hours claimed on the box! I am also engaged in several University Research studies, one of which is chronic pain, and we are investigating the use of metered dosage nasal sprays with three analgesics whose IN bioavailability is significantly higher than by any other route, the most extreme being oxymorphone HCl. We are also looking at hydrocodone bitartrate as a good drug to fill our 'analgesic gap', between dihydrocodeine and morphine salts there is nothing available in potency. At six times the potency of the codeines, hydrocodone (more correctky dihydrocodeineone) is almost slap bang in the middle of the two and as such could help thousands upon thoisands for whom the first is too weak and the second too strong for a long term Rx. Are there no sources who can supply these drugs for research purposes? There does not appear to be a single online pharmacy or wholesaler that will ship outwith the US, yet US consumers can buy from almost anywhere worldwide. If anyone knows of perhaps another University who will send such things, according to convention and Law, Research is exempt from all licencing and other regulatory constraints; this, however, seems to be ignored by the US, the only country I know of where clinical and research matters are given the jurisdiction of a LAW enforcement agency (DEA) who are permitted to interfere in what are MEDICAL matters. Even to the extent of preventing a doctor from following the Hippocratic Oath - I have first hand knowledge of a terminal patient refused his necessary - nay, ESSENTIAL - medications and his doctor threatened for using good professional judgement. I fimd that unacceptable - can anyone suggest where high dosage hydromorphome ( 4 & 8mg) and Endo Opana 10mg/Global oxymorphone 40mg ER might be obtained in enough quantity to treat around 100 patients for two months? Macfarlan Smith and Johnson Matthey no longer offer oxymorphone or hydrocodone here, only to US clients. MAny thanks for any advice.